Answer and Explanation:
The Huntington disease is caused by a mutation in the gene that codifies for the Huntingtin protein (Htt). The mutation produces an altered form of the protein leading to the neuron´s death in certain areas of the brain.
The Huntington disease characterizes for being,
- Hereditary, passing from generation to generation. To express the disease, a person must have been born with an altered gene.
- Autosomal, affecting men and women equally, because the mutated gene is located on an autosomal chromosome.
- Dominant, which means that by getting only one copy of the altered gene coming from any of the parents, the receiving person will express the disease. The mutation in the gene dominates over the normal gene copy.
- Expressed by heterozygosis. Most people affected by the disease are heterozygous, with a normal copy and a mutated copy.
There are just a few cases all around the world (3% approximately) in which the disease is expressed with no family history. The progenitors are not affected by the mutation. These cases are very rare and are called <u>"de-novo" mutations.</u> A new mutation is spontaneously produced and it is not inherited from any of the parentals. It consists of an increase in the number of CAG repetitions. In a normal person, the number of CAG repetitions is less than 35. When there are 40 or more repetitions it occurs the disease. But when there are between 35 and 39 repetitions, the penetrance of the disease is incomplete. This is a "gray zone". Those alleles that fall in the gray zone are unstable and might produce the HD. Individuals with these unstable alleles have a tendency to increase the number of repetitions from generation to generation until the number reaches 40 repetitions and the person expresses the disease. This <u>usually occurs in the paternal germinal line</u>, as it is particularly unstable in sperm and probably meiosis greatly affects their instability, causing an increase in the number of CAG repeats.
Answer:
<u>the genotype is (Hh)</u> <u>phenotype hybrid which is a Guinea pig with hair</u>.( hybrid means its not a pureblood haired Guinea pig. pureblood means same. EX: (GG). Guinea pig with hair. its also known as heterozygous, and zygous.)
witch also means its heterozygous. there is no percentage chance for something to have a different genotype of phenotype.
So we know that to transport materials in or out of the cell, we need to have access to both the inside and outside of the cell. This would require that the protein be a transmembrane protein that reaches both the inside and the outside of the cell.
So in this case, let's look at pore proteins. These are proteins that cross a membrane and act as a pore for the materials that need to cross the membrane.
One example of a pore protein is an aquaporin. These proteins aid in the transport of water into or out of a cell.
Therefore, the answer to your question is: A) Pore proteins.
Answer:
Option-C
Explanation:
Traditional ecological knowledge is the knowledge acquired and adapted by the local or native people living in a particular area.
The traditional knowledge is gained by the holistic approach of gaining the knowledge that is which benefits survival and increases the chances of well being.
The approach aims at learning by making direct contact with the surrounding environment, learning its ways, understanding the relationship between the various factors and then adapting to the condition and utilizing the available information.
The traditional way aims at looking at the environment in whole but the modern way of understanding the environment aim by learning the environment in the components.
The traditional knowledge is always shared by the local people in their local language but since the ideology of gaining the knowledge differ in both the ways and TEK is shared in local language therefore sometimes the knowledge does not prove useful in the contemporary world.
Thus, Option-C is correct.
