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OLga [1]
2 years ago
5

A DNA segment in a somatic cell undergoes the mutation shown;

Biology
1 answer:
klio [65]2 years ago
8 0

Answer:

This represents a <u>frameshift</u> mutation.

Explanation:

The difference between the two sequences is that there is an extra base (C) in the second sequence. A frameshift mutation occurs when there is an insertion or deletion of a nitrogenous base into a DNA sequence.

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1.) You are studying P120, a protein of 120 KDa that is continuously synthesized in eukaryotic cells. Its cellular concentration
irina1246 [14]

Answer:

1. P120 is degraded in the 26S proteasome

2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis

3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways

Explanation:

The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).

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What are reasons scientists use models?
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To study objects that are way too small

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This area on earth extends from 66.5o degrees North and south of the equator to the poles. It is an area on earth where temperat
Nataliya [291]

Polar ice cap

Explanation:

The polar ice cap is an area on the earth that extends from 66.5° north and south of the equator to the poles.

The polar ice cap is an area of very low temperature and the surface is mostly covered by ice.

  • The vast polar ice caps the earth's northern and southern limits.
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  • The region of the equator has no ice because they receive direct sunlight.
  • The soil here is frozen.

learn more:

Tundra brainly.com/question/2334099

#learnwithBrainly

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