· In 1775, the now-legendary frontiersman Daniel Boone blazed a trail through the Cumberland Gap–a notch in the Appalachian Mountains located near the intersection of Kentucky, Virginia and Tennessee–through the interior of Kentucky and to the Ohio River.
Its not A or C, and I don't think its B either so I'm pretty sure its D because I have never heard of U.S. District court. I just know for a fact that court of appeals and supreme court are part of the system. Superior court sounds familiar too. Its been a while since I took government, sorry.
Answer:
The diffusion of crops and pathogens, including epidemic diseases like the bubonic plague, often occurred along trade routes.
The bubonic plague - named the Black Death by later historians - was caused by the Yersinia pestis bacteria, which lived in rodent populations and was spread by fleas that had bitten infected animals.
Once the plague transferred to animals that were in close contact with humans and to humans themselves, it began to spread along established trade routes.
It is difficult to measure the exact human cost of the plague due to limited records from the historical period.
Most historians think that the plague killed somewhere between 30% and 60% of Europe’s population between 1347 and 1351.
Explanation: