Radiation sickness due to the effects of the bomb, Japanese citizens experiencing flash burns to the skin, and black rain coming from the sky are all short-term effects of the U.S.'s decision to drop atomic bombs over Japan. A long term effect is the acceptance of the Three Non-Nuclear Principles.
I think the answer is option 1
It left Burgoyne low on supplies and with no British forces to help.
Generally speaking, the federalists were led by Alexander Hamilton and John Adams, while the Dem-Rep's were led by Thomas Jefferson and James Madison. Hamilton and Jefferson being the more primary leaders, despite Adams and Madison also claiming the presidency and leading their respective parties during those times. Alexander Hamilton was never president, but stood as one of the most influential founding fathers who never gained the office of the presidency (alongside Benjamin Franklin).