The characteristics of Wernicke encephalopathy are;
- ophthalmoplegia,
- ataxia,
- confusion
<h3>What is alcoholism?</h3>
The term alcoholism refers to a situation in which a person takes in alcohol excessively to the point that it begins to result in certain health challenges.
There are three signs that usually characterize the irreversible development of Wernicke encephalopathy which are;
- ophthalmoplegia,
- ataxia,
- confusion
Learn more about alcoholism:brainly.com/question/4698220
#SPJ12
Signs and symptoms of having periodontists are Swollen or puffy gums, Bright red, dusky red or purplish gums, Gums that feel tender when touched, Gums that bleed easily, Pink-tinged toothbrush after brushing, Spitting out blood when brushing or flossing your teeth, Bad breath and Pus between your teeth and gums.
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Please include the multiple choice questions and/or a photo!
