Umm that really is a lot of words there but I will try to find a explanatory answer
Long-term potentiation (LTP) is considered a cellular correlate of learning and memory. The presence of G protein-activated inwardly rectifying K(+) (GIRK) channels near excitatory synapses on dendritic spines suggests their possible involvement in synaptic plasticity. However, whether activity-dependent regulation of channels affects excitatory synaptic plasticity is unknown. In a companion article we have reported activity-dependent regulation of GIRK channel density in cultured hippocampal neurons that requires activity oF receptors (NMDAR) and protein phosphatase-1 (PP1) and takes place within 15 min. In this study, we performed whole-cell recordings of cultured hippocampal neurons and found that NMDAR activation increases basal GIRK current and GIRK channel activation mediated by adenosine A(1) receptors, but not GABA(B) receptors. Given the similar involvement of NMDARs, adenosine receptors, and PP1 in depotentiation of LTP caused by low-frequency stimulation that immediately follows LTP-inducing high-frequency stimulation, we wondered whether NMDAR-induced increase in GIRK channel surface density and current may contribute to the molecular mechanisms underlying this specific depotentiation. Remarkably, GIRK2 null mutation or GIRK channel blockade abolishes depotentiation of LTP, demonstrating that GIRK channels are critical for depotentiation, one form of excitatory synaptic plasticity.
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Answer:
The right answer to this question is: 310k
Explanation:
There's a very good formula that can help us to find this answer, but first, we need to know the temperature scale in Celsius and Kelvin, there's an image below that will help us gather information.
The formula is quite simple, check it below:
C/5 = K-273/5
putting the values we already have in the formula it would be like this:
37/5 = K-273/5
Cutting out the fives, we can have the final result
37= K-273
37+273 = K
K= 310.
Another difference would be that DNA contains the 5 carbon sugar deoxyribose while RNA usually contains the 5 carbon sugar of ribose. One differs from the other, as ribose has an additional hydroxyl group bonded to one of the carbon atoms, where as deoxyribose does not.
