Question

Due to the speed of the response involved, the body's first line of defense against shifts in pH is its ______ buffer systems.

Answer 1

The body's first line of defence against shifts in pH is its acid-base buffer systems.

What is acid-base buffer system?

• The proper balance between the acids and bases in the body's extracellular fluid is crucial for the normal physiology of the body and for cellular metabolism.
• The first lines of defence are immediate, consisting of the various chemical buffers which minimize pH changes that would otherwise occur in their absence.
• The pH of the intracellular fluid and the extracellular fluid need to be maintained at a constant level.
• Proteins are denatured i.e. their 3D structure is disrupted, causing enzymes and ion channels to malfunction.

• An acid–base imbalance is known as acidaemia when the pH is acidic and alkalaemia when the pH is alkaline.

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