Similar to the conversion of pyruvate to acetyl-CoA, each pyruvate molecule loses a carbon atom with the release of carbon dioxide. During the decomposition of pyruvate, electrons move to NAD + to produce NADH. It is used by cells to produce ATP.
NADH: Three molecules are produced in the Kleb circuit
FADH2: One molecule is produced in the Kleb circuit
ATP or GTP: From each molecule of pyruvate during the conversion of succinyl-CoA to succinic acid Two molecules of ATP are produced. The presence of the enzyme succinyl-CoA synthetase.
