The word that best replaces curious in the sentence is ;
The word curious refers to the act of being eager to find out the details about something. It is synonymous with the word interested which also connotes the eagerness to learn about something.
Andy's curiosity refers to his interest in trying to see how bread was made. Thus the statement can be rewritten this way;
Andy was<u> </u><u>interested </u>to see how bread is made.
This replacement leaves the sentence with the same meaning. Therefore, the word that serves as the best replacement is interested.
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The answer to the question that is being presented above would be the second statement. The line that supports the idea that microbes are beneficial to humans are 's<span>ome microbes may help us deal with stress, or adapt to changes.'. </span>