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Diano4ka-milaya [45]
2 years ago
7

How can databases of variants be used to help pinpoint a disease-causing mutation?

Biology
1 answer:
wel2 years ago
8 0

The human gene mutation database (HGMD) is a collection of published germ-line mutations in nuclear genes that underlie , or are closely associated with human inherited disease.

For identifying the pathogenic mutation among thousands to millions of genomic variant is a major challenges and prioritization strategies are required. Current strategies for Mendelian disease gene identification by exome re-sequencing.

Next generation sequencing (NGS) has been  used to identify new pathogenic mutations and genes causing rare genetic diseases.  The analyses of NGS data is not trivial and required a technically and biologically rigorous pipeline that address the data quality , accurate variant filtration to minimize mistakes.

To learn more about  pathogenic mutation here

brainly.com/question/20115738

#SPJ4

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What episode wiped out many insect species in the world?
igomit [66]
The answer is Permian-Triassic extinction.

The Permian-Triassic extinction was 252 million years ago. It is known as The Great Dying because about 95% of all species died out due to environmental changes (volcanic eruptions, dry climate, melting of ice sheets, etc). This is also the only event in which many insect species wiped out.
6 0
3 years ago
Which statement about DNA is NOT correct?
drek231 [11]

Answer:

B (2nd Option): DNA is single-stranded

Explanation:

A is correct: DNA is indeed found in the nucleus of eukaryotes.

B is incorrect: Although there can be single strands of DNA (ssDNA), DNA is usually double-stranded which is how it forms its characteristic double-helix shape.

C is correct: Deoxyribose is indeed the sugar in DNA (Deoxyribonucleic Acid)

D is correct: The two single ringed nitrogenous bases in DNA are thymine and cytosine, while the other two (Adenine and Guanine are double ringed.

Hope this helped!

4 0
3 years ago
Lead poisoning can cause extensive organ/system damage, including: a. Respiratory failure, circulatory system collapse, and skin
adell [148]

Answer:

The correct answer will be option-C

Explanation:

Lead is a metal found in the Earth's crust which through human practices like using it in paints and other products cause lead poisoning in humans due to accumulation of lead in the body.

Lead poisoning can affect the child above 6 years and adults and prove harmful as its increased concentration can cause severe health problems common of which are the development of anaemia due to large consumption, brain damage, reduced mental growth and severe stomach ache.

Thus, Option-C is the correct answer.

4 0
3 years ago
Animal cells have all of the following except
Vlada [557]

Answer:

C

Animals have a mitochondria, a nucleus, and a cell membrane, bu they do not have chloroplasts. You can only find chloroplasts in human and plant cells, not a animal's cell. Hope it helps!

3 0
3 years ago
Read 2 more answers
1. To understand DNA replication, we need to understand
soldier1979 [14.2K]

Answer:

So that each cell has a full copy of DNA

Explanation:

6 0
2 years ago
Read 2 more answers
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