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Alex_Xolod [135]
2 years ago
8

extracellular vesicles carry distinct proteotranscriptomic signatures that are different from their cancer cell of origin

Biology
1 answer:
Nookie1986 [14]2 years ago
8 0

The translation, controlled destruction, mRNA turnover, and transcription of proteins all affect the proteotranscriptomic landscape.

  • Extracellular vesicles (EVs) in circulation carry lipids, proteins, RNA, and DNA from the cell that produced them. As a result, EV-associated proteins and RNA have drawn a lot of attention as liquid-biopsy indicators.
  • However, it is still unclear how the proteo-transcriptomic landscape of EVs compares to that of their cell of origin.
  • The study present evidence that certain proteo-transcriptomes that are enriched by EVs do not linearly correlate with those that originate from those cells.
  • Study demonstrate the enrichment of short RNA (13–200 nucleotides) involved in cell differentiation, development, and Wnt signaling as well as endosomal and extracellular proteins by EVs. RNY3, vtRNA, MIRLET-7, and the corresponding proteins YBX1, IGF2BP2, and SRSF1/2 are carried by EVs.

Learn more about the Transcriptome with the help of the given link:

brainly.com/question/14783864

#SPJ4

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