Question

The decrease in reproductive function, resulting in a decrease in testosterone and inhibin secretion, is called?

Answer 1

The decrease in reproductive function, resulting in a decrease in testosterone and inhibin secretion, is called male Climacteric or andropause.

Inhibin is a protein secreted by the Sertoli cells in men and by the granulosa cells in women. It inhibits the synthesis and release of the follicle-stimulating hormone in the pituitary gland and reduces the hypothalamic LH releasing hormone content. The testes also produce inhibin B and anti-Müllerian hormone from Sertoli cells, and insulin-like factor 3 and estradiol from the Leydig cells..

The maintenance of inhibin production by the testis requires the support of pituitary hormones, presumably FSH, while seminiferous tubule fluid production requires testosterone, presumably through LH stimulation of Leydig cells.

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