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Mila [183]
2 years ago
13

Prions are infectious particles that can cause normal proteins to assume a misfolded shape. when the proteins assume an abnormal

three- dimensional shape, they:_________
Biology
1 answer:
grandymaker [24]2 years ago
6 0

<u>Lose their function</u>.

Prions are infectious particles that can cause normal proteins to assume a misfolded shape. when the proteins assume an abnormal three- dimensional shape, they <u>lose their function.</u>

<u></u>

<h3>What causes misfolding in prions?</h3>
  • Transmissible spongiform encephalopathies are linked to the human prion protein's (PrP) abnormal folding and aggregation (TSEs).
  • The transformation of PrP from its cellular form into its pathological scrapie conformation produces intermediate conformations, which are a significant factor in the misfolding process.

<h3>Protein shapes are they altered by prions?</h3>
  • Normal PrPC proteins can be transformed into the infectious isoform by the infectious isoform of PrP, also known as PrPSc or simply the prion, by changing their conformation, or shape, which then changes how the proteins attach to one another.

<h3>How can misfolded proteins called prions spread disease?</h3>
  • The self-replicating isoform of the endogenous prion protein, PRP(c), which binds to the cellular PRP and transforms it into the infectious self-replicating form, is thought to be the mechanism that creates prions.

To learn more about prions visit:

brainly.com/question/13574637

#SPJ4

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goldenfox [79]

<u>Answer and Explanation</u>:

In reptiles, there are two mechanisms of sex determination:

-Genetic mechanisms, determined at the fertilization moment

-Environmental mechanisms, which are temperature-dependent.

Temperature is an environmental factor that affects different processes in organisms at a molecular level, biochemical level, or physiological level. In reptiles such as lizards, snakes, turtles, crocodiles, among other, temperature influences their embryonary development, their growth, daily activities, reproduction rate, sex determination, and etc.

In lizards, it occurs that whenever eggs are incubated at low temperatures, between 22 º and 27ºC, they produce a higher percentage of males, while eggs exposed to higher temperatures, 30ºC and above, produce more females. There are only a few degrees of temperature at which exposed eggs produce males and females equally.

The importance of knowing the mechanism of organisms´ sex determination lies in how climate change may be affecting wild populations due to fluctuations in temperature.

In the exposed example, the first cross between ZZ males and ZW females, genetics is the mechanism that determines the sex of progeny produced from eggs incubated at 24 and 35 degrees celsius. While in the second cross between ZZmales and ZZ females, temperature determines the sex of progeny produced from eggs incubated at 24 and 35 degrees celsius. This is, eggs exposed to temperatures below 28ºC will produce only males, so there won't be any female in the progeny. But eggs incubated at 30ºC and over will produce females, as shown in the table.

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jek_recluse [69]

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