Question

Sealants for preventing and arresting pit-and-fissure occlusal caries in primary and permanent molars: A systematic review of randomized controlled trials-a report of the American Dental Association and the American Academy of Pediatric Dentistry commentary

Answer 1

Sealants are superior to control without sealants or fluoride varnishes in terms of effectiveness and safety in halting or preventing the progression of non-cavitated carious lesions. To learn more about the relative qualities of the various kinds of sealant materials, more research is required.

Sealants had a lower risk of developing carious lesions in the occlusal surfaces of permanent molars than those who did not (odds ratio [OR], 0.15; 95 percent confidence interval [CI], 0.08-0.27). The authors discovered that sealants decreased the incidence of carious lesions after 7 or more years of follow-up when they reviewed studies whose researchers had compared sealants with fluoride varnishes (OR, 0.19; 95 percent CI, 0.07-0.51); however, this finding was supported by low-quality evidence. The authors were unable to establish a hierarchy of efficacy among the studies whose researchers had made side-by-side comparisons based on the available evidence.

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