Question

A channel protein, but not a carrier protein, can exist in a open configuration creating a pore through a membrane. True or false?.

Answer 1

The given statement is true.

• On one side of the membrane, carrier proteins bind to molecules or ions and release them on the opposite side.
• In order to allow target molecules or ions to diffusely pass through the membrane without interfering with one another, channel proteins make holes/pores that permeate the membrane.
• The specific solute to be transported is bound by carrier proteins (also known as carriers, permeases, or transporters), which then go through a series of conformational changes to move the bound solute across the membrane.
• In contrast, channel proteins have significantly weaker interactions with the solute being conveyed.
• While some channel proteins are always open, others are "gated," which means that they respond to a specific stimulus to either open or close the channel (like an electrical signal or the binding of a molecule).
• Transport proteins known as channel proteins contain a hydrophilic channel via which specific molecules or ions can pass across the membrane (Ex: aquaporins for water). Transport proteins known as carrier proteins bind to molecules and modify their structure to move them across the membrane.

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