Question

igf2bp3 enhances an aggressive tumor cell phenotype by impairing mirna-directed downregulation of oncogenic factors

Answer 1

Although the oncofetal IGF2 mRNA binding proteins (IGF2BPs) are increased in the majority of malignancies, little is known about the unique functions of their paralogues in tumour cells. IGF2BP1 exhibits significantly conserved carcinogenic potential in a panel of five cancer-derived cell lines.

What are Tumor cells ?

A mass of tissue that develops abnormally when cells do not die on schedule or expand and divide more often than they should. Cancer-free tumours might be benign or malignant (cancer). Although benign tumours can become enormous, they do not penetrate or spread to surrounding tissues or to other areas of the body.

• Tumors, which are tissue masses, can develop from these cells. Tumors may or may not be malignant (benign). Cancerous tumours can move to distant parts of the body to produce new tumours, invade neighbouring tissues, or both (a process called metastasis). Malignant tumours are another name for cancerous tumours.

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