The Gold Rush of 1848 negatively impacted the Native Americans. The Gold Rush caused large swaths of gold-seekers to settle in the Midwest and West--causing disruption. 
        
             
        
        
        
It's leaders knew it could not win the war.
        
                    
             
        
        
        
Answer:
1. developing humane treatment for the mentally ill
2. establishing hospitals for the mentally ill
 
        
             
        
        
        
The <span>Sierra Madre Oriental mountain range.</span>