Question

An illness is affecting the production of a ligand. Describe the processes on and in the cell that would be affected. A full credit answer to this question will list all possible ways a ligand interacts with a cell, and it lists all possible results of cellular response that could be disrupted. What kind of a ligand is it? What could be a cause of a change in production (there are many, name at least one)?

Answer 1

Receptors in the cell surface bind to their specific ligand and thus trigger a signaling pathway such as a phosphorylation cascade.

What are cell receptors?

Cell receptors are specific proteins within the cell membrane of the cell that binds to ligands and trigger signaling pathways, thereby mutations in the receptor sequence or problems associated with this process may produce a failure in the pathway.

The possible results of cellular response that could be disrupted include the inactivation of the signaling pathway, which might be a cause of a change in the production of a transcription factor that shapes gene expression patterns.

The types of ligands depend on the cell receptor (i.e., ion receptors, GPCRs, enzyme-based linking).

In conclusion, receptors in the cell surface bind to their specific ligand and thus trigger a signaling pathway such as a phosphorylation cascade.

Learn more about cell receptors here:

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