Question

The cAMP receptor protein (CRP) is said to be responsible for positive regulation of the lac operon because ________. (A) CRP binds c AMP (B) CRP binds to the CAP-binding site (C) CRP prevents binding of the repressor to the operator (D) CRP bound to the CRP-binding site stimulates the transcription of the lac operon

Answer 1

The cAMP receptor protein (CRP) is said to be responsible for positive regulation of the lac operon because (D) CRP bound to the CRP-binding site stimulates the transcription of the lac operon.

CRP is a regulatory protein. It binds to the cAMP and causes a conformational change. This allows the CRP to bind to a specific site at the promoter region of the DNA. This then activates the transcription process.

Lac operon is a group of genes that allow the uptake of glucose in bacteria. There are four components of lac operon:  regulator gene, promoter gene, operator gene and structural genes. The machinery of operon is turned on the lactose itself.

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