Question

jacobs ij, menon u, ryan a, gentry-maharaj a, burnell m, kalsi jk, et al. ovarian cancer screening and mortality in the uk collaborative trial of ovarian cancer screening (ukctocs): a randomised controlled trial. lancet 2016;387:945–56

Answer 1

We included postmenopausal women aged 50 to 74 in this randomized controlled study from 13 locations across National Health Service Trusts in England, Wales, and Northern Ireland. Previous bilateral oophorectomy, ovarian cancer, greater risk of ovarian cancer in families, and active non-ovarian cancer were considered exclusion criteria. The trial management system verified participant eligibility and randomly assigned participants in blocks of 32 using computer-generated random numbers to either annual transvaginal ultrasound screening (USS), annual multimodal screening (MMS), or no screening in a 1:1:2 ratio. The main outcome was death from ovarian cancer by December 31, 2014, and it was determined by an outcomes committee that was blind to the randomization group, comparing MMS and USS separately with no screening.

To learn more about ovarian cancer here:-

brainly.com/question/25637266?referrer=searchResults

#SPJ4