1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Alex Ar [27]
2 years ago
11

as-120 overcomes resistance to atp-competitive fgfr inhibitors in patients with fgfr2 fusion–positive intrahepatic cholangiocarc

inom
Biology
1 answer:
lilavasa [31]2 years ago
3 0

TAS-120 helps the patients in becoming resistant to BGJ398 and FGFR2 mutations.

Anti-tumor activity has been observed in the patient with intrahepatic cholangiocarcinoma (ICC) that activates ATP-competitive fibroblast growth factor receptor gene fusions. This results in resistance and results in the development of mutation of FGFR2 kinase.

It was further reported in 4 patients with FGFR2 that they developed Debio 1347. It was due to the activation of TAS-120 that fight the FGFR2.TAS-120 is the inhibitor of FGFR and it is irreversible. In patients with FGFR2, an increase in the duration of FGFR inhibition, FGFR inhibitors can be sequenced in a planned manner along with the biopsy.

TAS-120 helps the patients in becoming resistant to BGJ398 and FGFR2 mutations.

To know more about mutation, refer to the below link:

brainly.com/question/9598940

#SPJ4

You might be interested in
How do sea anemone catch prey?
V125BC [204]

Answer:

Tentacles have specialised stinging cells called nematocysts. They use these to immobilise their prey so that the tentacles are then able to move the food into the mouth.

Explanation:

6 0
3 years ago
The hereditary material in corn plants can be altered by scientist so the plants produce more corn. which term identifies this p
Slav-nsk [51]

Answer:

Genetic engineering

Explanation:

So there's Environmental degradation ,Ecological succession

Genetic engineering , Selective breeding . and so all the other ones aren't related to the materiel in corn so that makes it Genetic engineering ing

6 0
2 years ago
Wanda is in labor. Which hormone is causing her uterus to contract for childbirth?
lakkis [162]
Oxytocin. It apparently kick starts labour and causes contractions.
7 0
3 years ago
Read 2 more answers
Experiment 2:
oksano4ka [1.4K]

Answer:

17%

Explanation:

3 0
3 years ago
With the ____, the statements in the loop are repeated as long as a certain condition is false.
Tems11 [23]
<span>With the do until structure, the statements in the loop are repeated as long as a certain condition is false. The do until structure is used in order to execute a block of statements in an unspecified number of times until a condition becomes true.</span>
6 0
3 years ago
Other questions:
  • Explain why different gametes produced by the same person can have different combinations of alleles for genes that are located
    12·1 answer
  • Pastel consists of pigment bound with a ______ binder.
    11·2 answers
  • Which person is most likely to be infected when exposed to foodborn pathogens
    5·1 answer
  • What is the function of the cellular structure labeled “A” in the diagram below.
    9·1 answer
  • Apply the principles of diffusion to explain what will occur after placing a dyed sugar cube in a beaker of water
    5·1 answer
  • The clearing of forests for construction and the pollution of ecosystems are both examples of
    8·1 answer
  • Help this is very confusing :C
    8·2 answers
  • Foliated metamorphic rocks have mineral grains that are randomly placed.<br><br> T<br> F
    5·2 answers
  • Anyone wanna help me ???????
    12·1 answer
  • When a pigment molecule in a light-harvesting complex absorbs a photon of light, what happens to its excited-state electron?.
    8·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!