Question

A patient is taking the nonsteroidal antiinflammatory drug indomethacin (indocin) as treatment for pericarditis. the nurse will teach the patient to watch for which adverse effect?

Answer 1

A patient is taking the nonsteroidal anti-inflammatory drug indomethacin (Indocin) as treatment for pericarditis. The nurse will teach the patient to watch for Nausea and vomiting.

What is pericarditis?

• An enlargement and irritation of the heart's delicate, sac-like membrane (pericardium).
• A viral infection or cardiac stroke are two possible causes of pericarditis.
• The cause is frequently unknown.
• Sharp, stabbing chest discomfort that may radiate to the left shoulder and neck is the most typical symptom.
• Pericarditis typically starts suddenly and ends quickly.
• Most cases are minor and resolve on their own most of the time.
• Medication and, in rare situations, surgery may be used as treatments for more serious conditions.
• Viral infections are frequently the cause of pericarditis, while the exact origin is frequently unknown.
• Following an infection of the digestive or respiratory systems, pericarditis can develop.
• Autoimmune diseases like lupus, scleroderma, and rheumatoid arthritis can lead to chronic and recurrent pericarditis.

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Answer 2

The attending nurse who administers NSAID Indomethacin must carefully watch out for nausea and vomiting in a clinical diagnosis of a patient with pericarditis.

Significance of Pericarditis with NSAIDs

Symptom alleviation is the goal of treatment for individuals with idiopathic or viral pericarditis.

• The cornerstone of treatment is nonsteroidal anti-inflammatory medications (NSAIDs).
• These medicines have comparable effectiveness, with the alleviation of chest pain occurring in around 85-90% of patients within days of therapy.
• Ibuprofen has the benefit of having few side effects and increasing coronary flow. Indomethacin has a minimal risk of side effects and decreases coronary flow.

A full-dose NSAID (aspirin, 2-4 g/d; ibuprofen, 1200-1800 mg/d; indomethacin, 75-150 mg/d) should be utilized; therapy should continue at least 7-14 days.

• To prevent an early recurrence, a full-dose NSAID should be continued until C-reactive protein (CRP) normalization, followed by a progressive reduction of the medication for another 1-2 weeks.

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