With 4 distinct nucleotides, the total combinations possible in a sequence of 6 nucleotides will be 4096.
Nucleotides are the monomeric units that are found in the DNA. A nucleotide is made of three constituents: a pentose sugar, nitrogenous base and a phosphate group.
In a codon triplet the total possible combinations are 64.
This can be verified as: 4 × 4 × 4 = 64.
Similarly for a sequence of 6 nucleotides:
Possible combinations = 4 × 4 × 4 × 4 × 4 × 4 = 4096.
With a total of 4 nucleotides, each place in the sequence can have any of the four nucleotides. This is the reason why 4 is multiplied 6 times to obtain the result.
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