Question

A cell contains DNA damage that causes it to undergo apoptosis before reaching mitosis. This cell had twice the amount of DNA for a cell of this type. During which checkpoint did this cell trigger apoptosis?

Answer 1

Answer:

G1 Checkpoint

Explanation:

Data indicates that the G1 checkpoint is activated in response to mitotic DNA damage in the presence of p53, and that the mitotic DNA damage response is connected to the G1 checkpoint by p53. If cells continue to possess damaged DNA, apoptosis is induced in a p53-dependent manner.