Answer:
The placenta is an organ that develops in your uterus during pregnancy. This structure provides oxygen and nutrients to your growing baby and removes waste products from your baby's blood.
The pathophysiology of dementia of the Alzheimer type is loss of volume of brain tissue as neurons deteriorate and die.
<h3>What is Alzheimer disease?</h3>
Alzheimer disease is a type of disease that affects the brain cells and it's otherwise called a neurosis.
It is a neurodegenerative disease that is characterized by dementia, that is initial memory impairment and cognitive decline.
Pathophysiology of a disease is the pathway that shows how the disease affects the physiology of the body systems.
The pathophysiology of Alzheimer's disease include:
- The beta-amyloid deposition and neurofibrillary tangles lead to loss of synapses and neurons,
- This results in gross atrophy of the affected areas of the brain leading to death of brain cells.
Therefore, the pathophysiology of dementia of the Alzheimer type occurs due to beta-amyloid deposition which leads to loss of volume of brain tissue.
Learn more about dementia here:
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Pernicious anemia produces red blood cells that are <u>large</u> and<u> vitamin B12</u> deficiency contributes to pernicious anemia.
Explanation:
When there is a lack of intrinsic factor, secreted in the parietal cells of the gastric mucosa or the stomach lining, vitamin B12 absorption from the stomach is affected.
Vitamin B12 is one of the key factors responsible for normal synthesis and maturation of fully functional red blood cells (RBCs).
The main function of the RBCs is to carry oxygen through hemoglobin to all parts of the body. In order to transport oxygen, the RBCs must be mature with normal shape (concave center and circular shape) and size.
When there is a lack of vitamin B12, the RBCs are not matured and immature, megaloblastic, large, irregularly-shaped red blood cells are formed and circulate in the blood. This also leads to macrocytosis of RBCs.
These cannot function as normal mature blood cells because of the irregular shape and cannot carry hemoglobin to transport oxygen.