pooled image-base screening of mitochondria with microraft isolation distinguishes pathogenic mitofusin 2 mutations | communicat

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1 year ago

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ions biology (nature)

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Genrish500 [490] · Answer 1 · 2024-06-03T10:20:53+03:00

Screening of mitochondria which is pooled image-based with micrograft isolation distinguishes pathogenic mitofusion to mutations.

<h3>What is pooled screening?</h3>

More complicated strategies were needed for pooled screening platforms that include complex traits only visible under a microscope. There are a few methods for maintaining information about the cell's physical location, which is necessary for mapping phenotypic to disruption.
Using customized non-commercial sequencing rigs, some platforms use in situ sequencing (ISS) to produce sequencing findings that include positional data of a particular cell. Other technologies use targeted cells to photoactivate endogenous fluorophores, which are then subjected to FACS-seq.

<h3>What is Mitochondria?</h3>

Mitochondria is termed as the power house of the cell as it provides the energy and power to the overall cell.

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