Screening of mitochondria which is pooled image-based with micrograft isolation distinguishes pathogenic mitofusion to mutations.
<h3>What is pooled screening?</h3>
More complicated strategies were needed for pooled screening platforms that include complex traits only visible under a microscope. There are a few methods for maintaining information about the cell's physical location, which is necessary for mapping phenotypic to disruption.
Using customized non-commercial sequencing rigs, some platforms use in situ sequencing (ISS) to produce sequencing findings that include positional data of a particular cell. Other technologies use targeted cells to photoactivate endogenous fluorophores, which are then subjected to FACS-seq.
<h3>What is Mitochondria?</h3>
Mitochondria is termed as the power house of the cell as it provides the energy and power to the overall cell.
