Question

in reactions mediated by protein kinases what does phosphorylation of successive proteins ddo to drive the reaction

Answer 1

Phosphorylation of successive proteins drives the reaction by causing the proteins to change shape. The proteins can then bind to each other, or to other molecules, more tightly.

This increased binding affinity allows the proteins to work together more efficiently to drive the reaction.Protein kinases are enzymes that phosphorylate other proteins. Phosphorylation is the addition of a phosphate group to a protein. This modification can change the activity of the protein. Protein kinases are important in many cellular processes, including cell division, cell signaling, and cell death.

Protein kinases can phosphorylate multiple proteins in a cascade, which is a series of reactions in which each reaction is catalyzed by a different enzyme. The phosphorylation of successive proteins in a cascade can amplify the signal that is being transmitted.

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