In the depolarization step of action potential where the membrane resting potential is reversed by the rush of sodium ions into a neuron.
A membrane potential shift from -70mV to +30mV for a limited period of time is known as an action potential.
The moving action potential has three stages:
1) The depolarization step, where sodium ions rush into a neuron and reverse the membrane resting potential; and
2) repolarization, which is a mechanism that restores the resting voltage of the membrane and the ionic concentration in the cell, is caused by the closure of the voltage-gated sodium channels and the opening of the potassium channels.
3) Hyperpolarization, when excessive potassium ion efflux occurs as a result of some open potassium channels increasing potassium permeability and causing a drop in the membrane potential.
4) The action potential, which is a transient reversal of membrane potential that travels through the axon, comprises three phases that are described above.
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