A chemo sensitive region, which is particularly sensitive to CO2 and hydrogen ions, is located near to the rhythm center.
Increases in these compounds can activate this center, which can then tell the rhythm center to make the appropriate modifications in the respiratory process to remove these toxins.
The respiratory rhythm center
is a specialized center in the brain's medulla that is largely responsible for the control of breathing. A chemosensitive region near the rhythm center is extremely sensitive to changes in CO2 and hydrogen ion concentrations in the blood.
It is concluded that the mammalian central chemoreceptor for respiratory control is responsive to H+ and CO2 independently, and that the effects of H+ and CO2 on the respiratory center differ in frequency and magnitude.
It is proposed that frequency and magnitude (tidal volume) modulation for respiratory control are triggered at different regions of the respiratory center and/or rely on different mechanisms.
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