Karma there’s good karma and bad karma
After the death of Marcus Aurelius, the Roman empire slowly started to decline. Potential new emperors began to focus on pleasing the rich Patricians at the expense of the poor plebeians . The resulting decadence was just one reason for the fall of the empire.
(It needs to be pointed out that as the question seems incomplete and lacks more context, the answer might not meet the its standards).
The leaders of the dynasties are many, as dynasties last much longer than human life. It would mostly be the Chinese emperor of th time.
If you mean the founders: the founder of the Han was emperor Gao (previously rebel leader Liu Bang) and the founder of Qin was Duke Xiang, a leader of a war expedition.