(4) organic catalysts
The job of catalysts in chemical reactions is to make the reaction go faster by lowering the amount of energy needed to activate the reaction. If less energy is needed for the reaction to occur, then the reaction can go faster because a large energy build-up is not needed.
Microbes. Bacteria, for example, convert nitrogen and carbon dioxide from the air into usable components that plants and animals can use as essential building blocks. A loss of all microbes would be terrible news for living organisms that can't create or take in these essential nutrients on their own.