Polydactyly is an inherited trait that results in extra fingers or toes. In the United States 0.1% of the population exhibits po
lydactyly. People with polydactyly have the genotype Pp, where P represents the allele that causes polydactyly and p represents the normal allele of this gene. Which of the following is true? a. There is not enough information to answer this question.
b. The two alleles, P and p are at approximately equal frequencies in the US population.
c. The P allele is less frequent in the US than the p allele.
d. The P allele is more frequent in the US than the p allele.
c. The P allele is less frequent in the US than the p allele.
Explanation:
If people with the heterozygous genotype "Pp" present polydactyly, only people with the genotype "pp" will not present polydactyly. Since 99.9% of the population do not exhibit polydactyly, then it can be concluded that the "p" allele is much more frequent in the US than the "P" allele.
Therefore, the answer is:
c. The P allele is less frequent in the US than the p allele.
The TCF transcription factor will bind <u>less</u> frequently with the cell's DNA, resulting in <u>decreasing</u> transcription."less, decreased
Active canonical WNT flagging outcomes in enlistment of β-catenin to DNA by TCF/LEF relatives, prompting transcriptional actuation of TCF target qualities.
The extra translation factors have been recommended to enroll β-catenin and tie it to DNA.
The genome-wide example of β-catenin DNA official in murine intestinal epithelium, WNT -responsive colorectal malignant growth (CRC) cells and HEK293 early stage kidney cells.
The two classes of β-catenin restricting locales.
The top notch speaks to most of the DNA-bound β-catenin and co-limits with <em>TCF4, the noticeable TCF/LEF relative in these cells.</em>
