Answer:
Helminths
Explanation:
Niclosamide is an anti-helminth drug. It works by inhibiting ATP generation in the mitochondria. ATP which is a major source of energy for cellular organisms is deficient thereby hindering or stopping metabolic processes and then death. Helminths in which Niclosamide is effective against include Pin worm, Round wo,Beef tapeworm( Taenia saginata) etc. The drug is taken orally.
There is no answer that is right except for C. Natural Selection.
Genetic Recombination doesn't change gene frequency;nor does migration. (Unless it's local)
Mutation could be the answer, but since mutations are too rare to really power Evolution, the only logical answer is Natural Selection.