The largest landlocked harbor in the world is B. San Francisco Bay. It is located in Northern California.
Mesoamerica is different from <span>Central America.
</span>Mesoamerica<span> is referring to a region up to the North of Mexico. In the South-West, it also covers the nowadays states of Belize.
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Hope this helps :)
B is the answer because......
In 60 years, from 1801 to 1862, the amount of cotton picked daily by an enslaved person increased 400 percent. The profits from cotton propelled the US into a position as one of the leading economies in the world, and made the South its most prosperous region.