Tay–Sachs disease is an autosomal recessive disorder. Homozygous recessive individuals lack a key enzyme called hexosaminidase A
, which presents as progressive mental and motor deterioration until death occurs around age 5. Heterozygous individuals, called Tay–Sachs carriers, develop no symptoms of the disease. Tay–Sachs disease was historically more prevalent within populations of Ashkenazi Jews, Pennsylvania Dutch, southern Louisiana Cajuns, and eastern Quebec French Canadians. Today, individuals descended from these populations are more likely to be Tay–Sachs carriers, but genetic testing within these populations has largely eliminated the occurrence of Tay–Sachs disease. For a randomly mating population, calculate the Tay–Sachs carrier frequency to three decimal points if 1 in 3600 individuals develops Tay–Sachs disease.
Nutrients are the chemical substances required by any organism to meet the basic requirements of life. The nutrient can be either organic or inorganic, but both are important for the organism.
Law of inertia, also called Newton's first law, postulate in physics that, if a body is at rest or moving at a constant speed in a straight line, it will remain at rest or keep moving in a straight line at constant speed unless it is acted upon by a force