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inessss [21]
3 years ago
9

Name one enzyme of glycolysis that catalyzes an essentially irreversible step: __________

Biology
1 answer:
Alenkinab [10]3 years ago
6 0

Answer:

Phosphofructokinase-1

Explanation:

Phosphofructokinase-1 catalyzes the phosphorylation of fructose 6-phosphate into fructose 1,6-bisphosphate. The reaction is exergonic with a large negative free energy change to make it essentially irreversible.  

Phosphofructokinase-1 is an allosteric enzyme with regulatory sites. Higher ATP concentration serves to inhibit the phosphofructokinase-1 by binding to the allosteric site of the enzyme and thereby reducing its affinity for the substrate (fructose 6 phosphate).

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