In the late 1400s and 1500s, the main reason for exploration in the New World was the need for alternate trade routes. They have no idea the Americas even existed, however.
Byzantium/Constantinople was conquered in 1451, but the empire continued to decline starting around the 18th or 19th centuries. It officially died in WWI. As for how long it was a major threat to Europe, the empire's prime was the 16th century, under Suleiman the Magnificent.
Answer:
Explanation:
a mark of disgrace associated with a particular circumstance, quality, or person.
"the stigma of having gone to prison will always be with me"