Many different types of mutations can occur within the body. Sickle cell anemia is a disease that occurs when a mutation in a ba
se pair of the hemoglobin beta gene causes a single replacement of the amino acid glutamic acid by the amino acid valine. As a result of this mutation, the individual’s blood cells take on a sickle shape under certain conditions and form clusters that can block blood vessels and cause organ damage. Which type of mutation causes sickle cell anemia?
A)silent
B)missense
C)insertion
D)frameshift
Missense mutation is the type of mutation that causes sickle cell anemia
A missense mutation is a type of nonsynonymous substitution in which the change of a single nucleotide (base pair) influences the genetic code and results in a codon that code for a different amino acid. This type of mutation can affect the function of the protein, and it is responsible for human diseases such as, sickle-cell anemia and Epidermolysis bullosa.