The 2nd one is the true statement.
It spread through the Roman empire
The correct answer is "true". After the demise of the Tyndale New Testament, Henry VIII, the then still Catholic King of England had promised in 1530 that a new official English Bible would be prepared in accordance to Catholic doctrine. In 1534 he severed all ties with the Roman Catholic Church and the project of an official English Bible was to create a more Protestant version of it which would not be done until 1568 with the Bishops' Bible.
The two all water routs towards the Orient, or better said South, Southeast, and East Asia were all around the continent of Africa.
The first route was going along the northern part of Africa, than through the northeastern part, down alongside the eastern part of the continent, and than making a turn to the east.
The second route, which was discovered because of the occupation of the Muslims of the waters of the first one and were requiring high taxes, was along side the whole of the western coast of Africa to its southernmost tip, and than making a turn towards northeast to its final destination.
