Question

Assuming the human genome is 3×109 bp and that the average insert size in the genomic libraries is 100 kb, how frequently will a clone representing myostatin be found in the genomic library made from muscle?

Answer 1

A clone representing myostatin would be found in the genomic library made from muscle approximately one time out of every sixty thousand. Under the given conditions, the human genome and average insert size, the frequency of that particular type of clone can be estimated to be very near the probability of 1/60,000. This can be expressed either in fraction form or in descriptive words and maintain the same level of meaning.