Question

Some insecticides interfere with the removal of acetylcholine from the synaptic cleft. what effect will this have on muscle contraction

Answer 1

The effect of insecticides will result in prolonged muscle contraction.   Acetylcholinesterases are the enzymes that catalyze the breakdown of acetylcholine (Ach) in the synaptic cleft. This normally occurs, after the Ach achieves its effects on its receptors. On the other hand, acetylcholinesterase inhibitors inhibits the acetylcholinesterase enzyme thereby increasing the level and duration of action of the neurotransmitter ACh. Acetylcholinesterase inhibitors are used as insecticides.