Question

Identify two places in the krebs cycle where a decrease in free energy is coupled with an increase in free energy

Answer 1

Kreb's cycle or the citric acid cycle is a part of cellular respiration involving a series of reactions to release stored energy by the oxidation of Acetly CoA.

The first step of the citric acid cycle shows a decrease in free energy which is coupled with an increase in free energy. It begins with the transfer of acetyl group from the acetyl CoA to form an oxaloacetate which further forms citrate. Acetyl CoA forming CoA shows a decrease in the free energy which is coupled with the conversion of the oxaloacetate into the citrate showing an increase in free energy.

Further, the conversion of citrate into α- ketoglutarate shows a decrease in the free energy which is coupled with the reduction of NAD+ to NADH showing an increase in free energy.

Answer 2

Krebs cycle is the sequence of reactions by which most living cells generate energy during the process of aerobic respiration. It takes place in the mitochondria, consuming oxygen, producing carbon dioxide and water as waste products, and converting ADP to energy-rich ATP.

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