Question

Demyelination results from issues associated with myelin producing cells. What is an example of a myelin producing cell in the cns?

Answer 1

CNS  

Explanation:

An example of a myelin producing cell in the CNS is oligodendrocyte

• The major function of oligodendrocytes is the formation of myelin
• Myelin acts as an insulator of axonal segments and is a prerequisite for the high velocity of nerve conduction
• Larger axons form thicker myelin
• During development, oligodendrocytes arise from precursors located in the sub-ventricular zone such as the sub-ventricular zone of the lateral ventricles for the cerebrum or the fourth ventricle for the cerebellum
• In the spinal cord, oligodendrocytes originate from the ventral regions of the neural tube and in the optic nerve they migrate into the nerve from the third ventricle
• It is the oligodendrocyte precursor cells which migrate to their destination where they then differentiate into the more mature oligodendrocytes
• The proliferation of the oligodendrocyte progenitor cells is controlled by a number of growth factors released predominantly from neurons but also from astrocytes such as platelet derived growth factor (PDGF) or fibroblast growth factor (FGF)