Is they are random changes I believe they should be mutations
An apple is not an organism, but the cells within it are
you answered your own question??? what
Answer: Closed
Explanation:
At resting membrane potential( RMP) sodium channels remained shut, this is because , previously in depolarisation,the voltage gated sodium channels were opened for sodium to diffuse into the Axon. However these channels closed after reaching their refractory period,s.
Therefore a change in the extracellular concentration of sodium will not open them