Answer:
It was significant because it was the largest city in Egypt for more than two thousand years, not to mention being the capital for about half the time. The city made major profit from overland connection between the Mediterranean Sea and the Red Sea.
Settlers were constantly taking more land than either they agreed for, or just what didnt belong to them, the Indians would fight back and lose in the end, they would shrink back and find more land, there would be peace for a little while, and then settlers would keep wanting more land
The amendment becomes part of the Constitution when it has been ratified by three-fourths (currently 38) of the states. This process has been used for ratification of every amendment to the Constitution thus far. Article V also provides for an alternative process, which has never been utilized.