Answer:
Explanation:
Acetylcholine is a neurotransmitter, an organic chemical that that functions in the body and brain.
It is one of the substance released by the nerve cell, so that it can send signal to cells such as;gland cell, muscle cell. Acetylcholine causes contraction of muscles and also regulates endocrine functions. Lack of acetylcholine in the body can results to muscle weakness.(myasthenia)
To Indicate whether each of the below conditions would increase or decrease the effect of acetylcholine.
A.) addition of a drug that stimulates the GTPase activity of the Gα subunit.
Answer: INCREASE
B.) mutations in the K+ channel that keep it closed all the time.
Answer: DECREASE
C.) modification of the Gα subunit by cholera toxin
Answer: INCREASE
The reason is because Toxin inhibit GTP hydrolysis
D.) a mutation that decreases the affinity of the βγ complex of the G protein for the K+ channel.
Answer: DECREASE
E.) a mutation in the acetylcholine receptor that prevents its localization on the cell surface
Answer: DECREASE
.
F.) adding acetylcholinesterase to the external environment of the cell
Answer: DECREASE
.
