The 3 major mountain ranges in the United States are the Pacific ranges and Rocky Mountains in the west and the Appalachian mountains in the east. The Pacific ranges are on the northwestern coast of the United States. The Rocky Mountains are in the western United States but east of the Pacific ranges. They extend all the way from Canada into Mexico and cover 8 states. The Appalachian Mountains are near the East Coast of the United States. They extend from Canada to Alabama. The main difference between the eastern mountain ranges and the western mountain ranges is their ages and heights. The Appalachian Mountain range is the oldest range in the United States. Because of this, the range has faced weathering and erosion, which has worn the mountains down. The highest peaks in the Appalachians are only 6,000 feet. The ranges in the west are much younger and in some cases still growing. The mountains in the west are much higher than those in the east, with peaks over 14,000 ft.
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Smallpox has had a major impact on world history, not least because indigenous populations of regions where smallpox was non-native, such as the Americas and Australia, were rapidly decimated and weakened by smallpox. During the 18th century the disease killed an estimated 400,000 Europeans each year, including five reigning monarchs, and was responsible for a third of all blindness. After successful vaccination campaigns throughout the 19th and 20th centuries, the WHO certified the global eradication of smallpox in December 1979. Smallpox is one of two infectious diseases to have been eradicated.
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