He was so exhausted with the bloodshed caused by his actions that he was almost immune to the pain of death.
Explanation:
Lady Macbeth's death left Macbeth in an extreme state of despair and misery. He wishes that she should have lived "hereafter" and speculates the brevity of life.<em> His soliloquy of "tomorrow and tomorrow" is representative of exhaustion of life and absorbed with self-pity. He was a man of hopes who has turned into a depleted individual who is now pondering the immortality and meaninglessness of life.</em>He was so distressed and taken aback by the carnage that death was now impotent to his immunity.