I think all of them provide strong evidence, but the best would probably be the last one.
Hope this helps
Answer:
Genotype
Explanation:
Phenotype refers to traits that physically appear, genotype refers to genetic traits
Protein Function may be terminated, disrupted, destruction of both the secondary and tertiary structure through the process called DENATURATION. Denaturation process does not break the primary structures since the link or sequence of peptide bond are greatly hold by Hydrogen bonding.