The layer of connective tissue, called the _perimysium_ , extends inward from the epimysium and separates the muscle tissue into small sections. these sections contain bundles of skeletal muscle fibers called _fascicles_ .
Additionally, bundles of contractile proteins called fibrils fill a muscle cell, called a fiber. Outside of each fiber, is the connective tissue endomysium. Bundles of fibers form fascicles, surrounded by perimysium. Bundles of fascicles and perimysium comprise the entire muscle organ, which is enclosed by epimysium.
Proteins that affect the structure of dna bound to histones without altering histone chemical structure are called Non-histone protein.
The proteins that remain after the histones have been taken out are known as non-histone proteins. A large group of heterogeneous proteins referred to as non-histone proteins organise and compress the chromosome into higher order structures.
They play a crucial role in regulating processes such nuclear transport, steroid hormone activity, nucleosome remodelling, DNA replication, RNA synthesis and processing, and the transition between interphase and mitosis.
Scaffold proteins, DNA polymerase, Heterochromatin Protein 1, and Polycomb are examples of typical non-histone proteins. This classification area also includes a large number of other structural, regulatory, and motor proteins. Non-histone proteins can be acidic. Other than histones, many proteins have the ability to bind to DNA and change the shape of the chromatin by means of epigenetic processes.
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